Organic acids and derivatives
eMolecules 401-67-2 | Difluoroacetic anhydride | Combi-Blocks | MFCD02093315 | 174.051 | C4H2F4O3 | 85.000 | FC(F)C(=O)OC(=O)C(F)F | 25g | 457920239
Difluoroacetic anhydride | Combi-Blocks | 401-67-2 | MFCD02093315 | 174.051 | C4H2F4O3 | 85.000 | FC(F)C(=O)OC(=O)C(F)F | 25g | 457920239
Medchemexpress LLC Pitavastatin-d5 sodium | 574705-92-3 | 99.5% | 1 MG
Pitavastatin-d5 sodium is the deuterium-labeled Pitavastatin sodium. Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor, inhibiting cholesterol synthesis with an IC50 of 5.8 nM in HepG2 cells. It also acts as an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer and exhibits anti-cancer activity.
- Can be used as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potent HMG-CoA reductase inhibitor
- Inhibits cholesterol synthesis from acetic acid
- Efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer
- Exhibits anti-cancer activity
Cayman Chemical Ac-DEVD-CHO (trifluoroacetate salt), Purity: ≥95%, 1 mg
A potent, reversible inhibitor of caspase-3 and caspase-7 (Kis = 0.23 and 1.6 nM, respectively); also inhibits other caspases (Kis = 18, 1710, 132, 205, 31, 0.92, 60, and 12 nM for caspases-1, -2, -4, -5, -6, -8, -9, and -10, respectively)
Cayman Chemical Pentosidine (trifluoroacetate salt), Purity: ≥98%, CAS: 225784-09-8, 10 mg
A well-characterized natural advanced glycation end (AGE) that is often used as a biomarker for the production of all AGEs
Cayman Chemical GSK121 trifluoroacetate salt
The initial compound identified in a screen for PAD4 inhibitors (IC50 = 3.2 µM in functional assay) that was optimized to produce the more potent PAD4 inhibitors, GSK484 and GSK199
AdipoGen Saquayamycin B1
Chemical. CAS 99260-68-1. Formula C31H32O12. MW 596.6. Isolated from Streptomyces nodosus. Angucycline antibiotic. Antibacterial. Antitumor compound. Active against Gram-positive bacteria and P388 leukaemia cells. Farnesyl-protein transferase inhibitor. Inhibitor of nitric oxide synthase NOS shown for Saquayamycin A1.
Cayman Chemical Pam2CSK4 trifluoroacetate sa
A bacterial lipopeptide and TLR2 agonist; selective for TLR2/TLR6 over TLR2/TLR1 (EC50s = 0.015 and 4.12 ng/ml, respectively, in reporter assays using human receptors); increases levels of iNOS and the production of NO in RAW 264.7 macrophages at 100 ng/ml; stimulates osteoclast formation, induces gingival inflammation, and decreases alveolar bone mass in a mouse model of periodontitis at 5 UG/animal; reduces parasite burden and enhances the response to antigen in a mouse model of lymphatic filariasis induced by B. malayi when used as an adjuvant at 10 UG/vaccine
Cayman Chemical W140 (trifluoroacetate salt), Purity: ≥95%, CAS: 909725-64-0, 1 mg
An inactive enantiomer of W146; binds weakly to S1P1 (Ki = 4.6 µM for the human receptor); has been used as a negative control in the study of S1P1 receptor signaling
Cayman Chemical MSG606 trifluoroacetate salt
A peptide MC1R antagonist (IC50 = 17 nM); selectively binds to MC1R over MC3R and MC5R (IC50s = 3,900 and 1,000 nM, respectively), as well as MC4R at 10 µM; increases the latency to tail withdrawal in the tail-flick test in female, but not male, mice in a model of opioid-induced hyperalgesia at 7.5 UG/animal, i.c.v.; reduces protein levels of merlin in the cortex, reduces the number of surviving neurons in the cortex and hippocampal CA2 region, and increases the number of apoptotic cells in the cortex in rats 24 hours after injury in a model of controlled cortical impact-induced TBI at 1 nmol/animal, i.c.v.
eMolecules 79-08-3 | Bromoacetic acid | Chem-Impex138.948 | C2H3BrO2 | 98.000 | OC(=O)CBr | 250g | 112766269
Bromoacetic acid | Chem-Impex | 79-08-3138.948 | C2H3BrO2 | 98.000 | OC(=O)CBr | 250g | 112766269
eMolecules 1878-67-7 | 2-(3-Bromophenyl)acetic acid | Synthonix - Stock | MFCD00004330 | 215.046 | C8H7BrO2 | 95.000 | OC(=O)Cc1cccc(Br)c1 | 100g | 495874663
2-(3-Bromophenyl)acetic acid | Synthonix - Stock | 1878-67-7 | MFCD00004330 | 215.046 | C8H7BrO2 | 95.000 | OC(=O)Cc1cccc(Br)c1 | 100g | 495874663
Selleck Chemical LLC Aminoguanidine hydrochloride S4548-500mg
Aminoguanidine (Pimagedine Guanyl hydrazine Hydrazinecarboximidamide Imino semicarbazide Monoaminoguanidine) is a diamine oxidase and nitric oxide synthase inhibitor It acts to reduce levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone